Vulvodynia is a general term meaning pain of any sort in any place at the vulva (outer vaginal area around the lips and clitoral hood.) Many women suffer greatly from lichen sclerosus and / or vestibulitis, which are specific auto-immune diseases that have no definite cause and no good cure to date. Frequent use of potent steroids is the best treatment known to treat these chronic, often debilitating conditions. lichen sclerosus is thick, dense, white or purplish skin around the clitoral hood, labia and outside the vaginal opening causing tight, contracted tissues. Vestibulitis is the inflammation of the many tiny glands right at the vaginal opening for which no great cure is known besides chronic steroids or surgery. The pain experienced with vaginal penetration and vestibulititis is often called the “Ring of Fire”. PRP may be able to calm down the inflammation and pain locally. Episiotomy and prior surgical sites often have chronic scars and irritation that can be alleviated with PRP at the central base of the vaginal opening where many women experience pain with sex.